와파린 효과에 영향을 주는 약물

와파린 효과에 영향을 주는 약물

 

May increase anti-clotting effect (and possibly increase risk of bleeding) : Left column	May decrease anti-clotting effect (and possibly increase risk of blood clots) : Right column
Antibiotics
Examples: Amoxicillin (brand name: Amoxil), amoxicillin-clavulanate (brand name: Augmentin), ciprofloxacin (brand name: Cipro), levofloxacin (brand name: Levaquin), metronidazole (brand name: Flagyl), trimethoprim-sulfamethoxazole (brand name: Bactrim); others
Antifungals
Example: Fluconazole (brand name: Diflucan); posaconazole (brand name: Noxafil), voriconazole (brand name: Vfend); others
Hormones
Examples: Methyltestosterone (brand name: Methitest), oxandrolone (brand name: Oxandrin), testosterone (brand names: Androderm, AndroGel, Axiron, Fortesta, Testim); others
Antidepressants or nerve pain	Antibiotics and anti-tuberculosis medications
Examples: Amitriptyline (brand name: Elavil), duloxetine (brand name: Cymbalta), fluoxetine (brand names: Prozac, Sarafem), sertraline (brand name: Zoloft), venlafaxine (brand name: Effexor); others	Examples: Dicloxacillin, nafcillin, rifampin (brand names: Rifadin, Rifamate, Rifater), rifapentine
Cancer	Cancer
Examples: Capecitabine (brand name: Xeloda), fluorouracil, imatinib (brand name: Gleevec); tamoxifen (brand name: Nolvadex, Soltamox); others	Example: Enzalutamide (anti-androgen, brand name: Xtandi)
Cholesterol	Cholesterol
Examples: Fenofibrate (brand name: Lofibra, Tricor, Trilipix, others), gemfibrozil (brand name: Lopid), most statin drugs (brand names include: Crestor, Lescol, Mevacor, Zocor)	Cholestyramine (brand names: Prevalite, Questran)
Gout	Herbs
Allopurinol (brand names: Aloprim, Zyloprim)	Example: St. Johns wort
Heart	Rheumatoid arthritis, transplant anti-rejection, control of immune system
Example: Amiodarone (brand names: Cordarone, Pacerone)	Azathioprine (brand name: Imuran)
Pain relievers and cough/cold medicines that contain aspirin or an NSAID	Seizures or nerve pain
Examples: Aspirin, celecoxib (brand name: Celebrex), ibuprofen (brand names: Advil, Motrin), naproxen (brand names: Aleve, Naprosyn), tramadol (brand names: Ultram, Ultracet); others Many over-the-counter pain relievers and cough/cold medicines contain an NSAID Always discuss all new medicines, including over-the-counter pain relievers and cough/cold medicines with your doctor	Examples: Carbamazepine (brand name: Tegretol), fosphenytoin (brand name: Cerebyx), phenobarbital (brand name: Luminal), phenytoin (brand name: Dilantin); others
Stomach and heartburn relief	Stomach and nausea
Cimetidine (brand name: Tagamet), omeprazole (brand name: Prilosec)	Aprepitant (brand name: Emend), fosaprepitant (brand name: Emend IV), sucralfate (brand name: Carafate)
Steroids (glucocorticoids)	Vitamin K
Examples: Methylprednisolone (brand name: Medrol, Medrol Dose Pack), prednisone, prednisolone (brand name: Orapred); others	Avoid vitamin K supplements except the small amount in a daily multiple vitamin ("multivitamin") pill. If you take a multivitamin be sure to take it every day. If you stop taking a multivitamin, let your doctor know.

This is only a partial list. Many other drugs can interact with warfarin. Always tell your doctor before starting or stopping any drug when you are on warfarin, including over-the-counter and herbs/natural supplements. You may need a blood test and a change in your warfarin dose when you start or stop another medicine that can interact with warfarin.

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