Effect of Dietary and Supplemental n-3 PUFA on Risk of Recurrent Gout Flares.

 

항염증작용이 있는 것으로 여겨지는 n-3 PUFA가 통풍 발작을 줄이는데 도움이 될 수 있습니다.

 

n-3 PUFA 가 풍부한 fatty fish를 섭취하는 것이 발작을 줄이는 것과 관련이 있었지만 단순 보충제는 더 낮은 위험과 관련이 없었습니다.

 

그 차이는 fatty fish보다 단순 보충제의 n-3 PUFA 함량이 훨씬 적은 것에 기인한 것 같습니다.

 

Purine이 풍부한 fish를 피하기 위해 고용량 단순 보충제로 통풍 발작 감소 효과가 있는지 여부는 연구가 필요합니다.

 

 

What's New

Effects of fish and omega-3 fatty acid consumption on gout flare risk (December 2019)

 

Omega-3 polyunsaturated fatty acids (n-3 PUFA), which are thought to have anti-inflammatory properties, might help reduce risk of gout flares.In an internet-based case-crossover study involving over 700 patients with gout, patient-reported dietary intake of fatty fish rich in n-3 PUFA was associated with reduced risk of a flare. By contrast, n-3 PUFA supplements alone (taken in a self-directed manner) were not associated with lower risk. This difference might be due to the much lower dose of n-3 PUFA usually taken as a supplement compared with the level in fatty fish. Whether higher-dose supplements may reduce risk, while serving as a means to avoid undesirable high levels of dietary purines in fish, remains to be examined before high-dose n-3 PUFA supplements can be recommended for gout flare prevention.

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REF. UpToDate 2020.04.12