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봉직, 개원/봉직, 개원

외래 진료10 [ Polycythemia vera]

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PV should be suspected in any patient with an increased red blood cell mass or increased hemoglobin/hematocrit and an arterial oxygen saturation >92 percent. To be considered for the diagnosis, men should have a hemoglobin level of at least 16.5 g/dL or a hematocrit level of ≥49 percent, and women should have a hemoglobin level of at least 16 g/dL or a hematocrit level of ≥48 percent. PV should also be suspected in patients with the Budd-Chiari syndrome and portal, splenic, or mesenteric vein thrombosis, particularly women under the age of 45. In this setting, the ensuing portal hypertension and hypersplenism may mask the increase in blood cell counts. Additional evidence suggesting the diagnosis of PV includes the following:

■ Splenomegaly

■ Thrombocytosis and/or leukocytosis

■ Thrombotic complications

■ Erythromelalgia or aquagenic pruritus

■ Microvascular symptoms (eg, headaches, paresthesias)

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