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내분비내과/갑상선기능저하증

갑상선기능저하증에서 부종, Edema in hypothyroidism

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C/C Facial edema (신체 다른 부위보다는)

Anemia Hb 12.6

R/O AKI Cr 1.34

CPK 1542

Dyslipidemia : Total cholesterol 397 mg/dL

Hypothyroidism : FT4 0.40, TSH > 100

​갑상선기능저하증에서 나타나는 피부변화는 다음과 같습니다.

● Sweating is decreased because of decreases in calorigenesis and acinar gland secretion.

● Skin discoloration may occur. A yellowish tinge may be present if the patient has carotenemia, while hyperpigmentation may be seen when primary hypothyroidism is associated with primary adrenal failure.

● Hair may be coarse, hair loss is common, and the nails become brittle.

Nonpitting edema (myxedema) occurs in severe hypothyroidism and may be generalized. It results from infiltration of the skin with glycosaminoglycans with associated water retention [1].

● Vitiligo and alopecia areata may be present in patients with hypothyroidism after treatment of Graves' hyperthyroidism.

대사율이 감소하고 fluid가 축적되면 (rich in glycosaminoglycans) 적당한 체중 증가(nonpitting edema)가 있지만 현저한 비만은 갑상선기능저하증 특징은 아닙니다. 이 환자의 facial edema는 약간의 anemia와 hypothyroidism 때문으로 여겨집니다.

참고로 외래로 내원하는 전신 부종의 가장 많은 원인 5가지는 다음과 같습니다.

1. Anemia ---> Blood test

2. Hypothyroidism ---> Blood test

3. Heart failure ---> Chest PA, echo

4. Kidney ---> Blood and urine test

5. Liver ---> Blood test, liver sono

REF. UpToDate 2020.03.07

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