Clinical risk factors for stroke, TIA, and systemic embolism in the CHA2DS2-VASc score

Clinical risk factors for stroke, transient ischemic attack, and systemic embolism in the CHA2DS2-VASc score

(A) The risk factor-based approach expressed as a point based scoring system, with the acronym CHA2DS2-VASc (NOTE: maximum score is 9 since age may contribute 0, 1, or 2 points)
CHA2DS2-VASc risk factor		Points
Congestive heart failure Signs/symptoms of heart failure or objective evidence of reduced left-ventricular ejection fraction		+1
Hypertension Resting blood pressure >140/90 mmHg on at least two occasions or current antihypertensive treatment		+1
Age 75 years or older		+2
Diabetes mellitus Fasting glucose >125 mg/dL (7 mmol/L) or treatment with oral hypoglycaemic agent and/or insulin		+1
Previous stroke, transient ischaemic attack, or thromboembolism		+2
Vascular disease Previous myocardial infarction, peripheral artery disease, or aortic plaque		+1
Age 65-74 years		+1
Sex category (female)		+1
(B) Adjusted stroke rate according to CHA2DS2-VASc score
CHA2DS2-VASc score	Patients (n = 73,538)	Stroke and thromboembolism event rate at one-year follow-up (%)
0	6369	0.78
1	8203	2.01
2	12,771	3.71
3	17,371	5.92
4	13,887	9.27
5	8942	15.26
6	4244	19.74
7	1420	21.50
8	285	22.38
9	46	23.64

CHA2DS2-VASc: Congestive heart failure, Hypertension, Age (≥75) (doubled), Diabetes, Stroke (doubled), Vascular disease, Age (65-74), Sex.

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Part A from: Kirchhof P, Benussi S, Kotecha D, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Europace 2016; 18(11):1609-1678. By permission of Oxford University Press on behalf of the European Society of Cardiology. Copyright © 2016 Oxford University Press. Available at: www.escardio.org/.

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REF. UpToDate 2019.08.25