여행자에서 일본 뇌염 백신 사용 권고사항, Recommendations for use of Japanese encephalitis vaccine in travelers

Recommendations for use of Japanese encephalitis vaccine in travelers

Recommendations:

JE vaccine is recommended for travelers who plan to spend a month or longer in endemic areas during the JEV transmission season. This includes long-term travelers, recurrent travelers, or expatriates who will be based in urban areas but are likely to visit endemic rural or agricultural areas during a high-risk period of JEV transmission.

JE vaccine should be considered for the following:

Short-term travelers (<1 month) to endemic areas during the JEV transmission season if they plan to travel outside of an urban area and have an increased risk of JEV exposure. Examples of higher risk activities or itineraries include: (1) Spending substantial time outdoors in rural or agricultural areas, especially during the evening or night; (2) Participating in extensive outdoor activities (eg, camping, hiking, trekking, biking, fishing, hunting, or farming); and (3) Staying in accommodations without air conditioning, screens, or bed nets.

Travelers to an area with an ongoing JE outbreak

Travelers to endemic areas who are uncertain of specific destinations, activities, or duration of travel

JE vaccine is not recommended for short-term travelers whose visit will be restricted to urban areas or times outside of a well-defined JEV transmission season.

Information on expected JEV transmission by country can be obtained from the CDC at http://wwwnc.cdc.gov/travel/yellowbook/2014/chapter-3-infectious-diseases-related-to-travel/japanese-encephalitis. These data should be interpreted cautiously since JEV transmission activity varies within countries and from year to year.

JE vaccine is also recommended for laboratory personnel with potential for exposure to infectious JEV. Vaccinated, at-risk laboratory personnel should receive appropriate booster doses of JE vaccine or be evaluated regularly for JEV-specific neutralizing antibodies to assure adequate titers.

JE: Japanese encephalitis; JEV: Japanese encephalitis virus; CDC: Centers for Disease Control and Prevention.

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REF. UpToDate 2019.05.10