생식기 헤르페스 감염, 재발율, Genital HSV infection, risk of recurrence

생식기 HSV 감염은 종종 빈번한 재발을 초래하는데 HSV2 재발이 HSV1보다 많습니다. 치료받지 않은 경우 재발이 많지만 첫 감염 때 치료를 받았을지라도 재발이 있을 수 있습니다. 그 이유는 latent virus까지 없애지 못하기 때문입니다.

Genital HSV infection often leads to frequent clinical recurrences, although the risk of genital recurrence is lower in those infected with HSV-1 versus HSV-2. Recurrences can occur even in those who were treated during their initial infection since treatment does not eradicate latent virus, which can subsequently reactivate. Over time, recurrences due to either viral type generally decrease in number and severity, although there is substantial variability in the clinical course from patient to patient .

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바이러스 치료를 하지 않으면 평균 재발율은 첫 HSV-2 감염 이후 1년에 4회입니다. 반면에 HSV-1 재발률은 1년에 약 1회입니다.

In the absence of suppressive antiviral therapy, the median recurrence rate after the first episode of HSV-2 infection is about four recurrences per year, with about 40 percent of patients having at least 6 recurrences and 20 percent having more than 10 recurrences in the first year. By contrast, recurrences of HSV-1 occur approximately once per year.

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REF. UpToDate 2020.05.08

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