Exercise induced bronchoconstriction(EIB), selection of pharmacologic therapy

 

운동유발성 기관지수축의 빠른 경감으로 가장 효과적인 치료는 SABA입니다. 2회 흡입으로 보통 충분합니다(예, 벤토린).

Short-acting beta-agonists (SABAs; albuterol[salbutamol], levabuterol) are the most effective therapy for quick relief of EIB. All patients who report exercise-related symptoms should have access to a SABA for quick relief and be instructed on correct technique. Two inhalations (eg, albuterol 90 mcg/inhalation) are generally sufficient; occasionally four inhalations are needed.

 

Ipratropium은 기관지확장이 지연되기 때문에(약물 작용 시작은 15분) 일반저긍로 사용되지 않습니다.

Ipratropium is generally notused for quick relief as bronchodilation is delayed (onset at 15 minutes and peak at 1 to 2 hours) compared with SABAs.

 

천식이 잘 조질되지만 빈번하게 운동을 하면 천식 증상이 악화되는 환자들은 운동 5-20분 전에 SABA, 2회 흡입을 하도록 합니다. Budesonide-formoterol(160 mcg/4.5 mcg) 흡입 1회를 해도 됩니다.

Patients who have well-controlled asthma, but frequently have asthma symptoms with exercise, should be instructed to use prophylactic treatment approximately 5 to 20 minutes before exercise, usually with two inhalations of a SABA (eg, albuterol, levalbuterol). An alternative is to use a combination budesonide-formoterol(160 mcg/4.5 mcg) inhaler, 1 inhalation 5 to 20 minutes prior to exercise.

 

 

REF. UpToDate 2020.02.01